Karuna DuoZyme is formulated to support basic digestion process of proteins, carbohydrates and fats. As we age digestive enzymes become more important and we see this in blood tests as reduced blood proteins and protein imbalances. Proper digestion requires both a gastric phase supplying hydrochloric acid and pepsin, and an alkaline duodenal phase supplying protease, amylase, and lipase enzymes. DuoZyme provides all of these factors in a single, convenient, high potency capsule delivery system. DuoZyme utilizes the technologically superior enzyme-release system which was favorably evaluated by Dr. David Graham in An Enteric-Coated Pancreatic Enzyme Preparation That Works (Dig Dis Sci 1979;24:906-9). DuoZyme contains the acidulants betaine HCl and glutamic HCl, which help acidify gastric contents, creating a favorable environment for the proteolytic action of pepsin. Pancreatin and ox bile extract, contained in pH-sensitive microspheres, supplement the natural secretions of the pancreas and liver, and promote the intestinal phase of digestion. pH-sensitive microspheres typically provide a more effective means for delivering intact enzymes to the small intestine to reduce malabsorption of macronutrients (Dig Dis Sci 1979; 24:906-9).
Suggested use for adults: Two or more capsules, taken with meals, or as directed by your healthcare professional.
Warning: patients with active peptic ulcer should use HCl products with caution.