Pure Encapsulations Folate 5,000 Plus
supports cellular, cardiovascular, neurological and psychological health. Provides the naturally occuring form of folate. Recommended Use:
1 capsule daily with a meal, or as directed by a healthcare professional.
- 5,000 mcg of activated folate per capsule
- Combination of activated B vitamins
- Made with hypoallergenic, vegan ingredients
What Is It? Folate is provided in this formula as 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate. This form is the predominant, naturally occurring form of folate in food. Through bypassing several enzymatic activation steps, it is directly usable by the body and provides all of the benefits of folic acid regardless of functional or genetic variations.
Uses for Folate 5,000 Plus Cellular Health:
Optimal levels of folate, vitamin B6, and vitamin B12 have been associated with cellular, cardiovascular, neurological and psychological health. 5-MTHF is the predominant, naturally occurring form of folate in food. As genetic variations affecting activation and metabolism of supplemental folic acid are highly prevalent, 5-MTHF bypasses several enzymatic activation steps, offering all of the benefits of folic acid regardless of functional or genetic variations. This form offers superior bioavailability and can be directly used in a diverse array of essential methylation reactions. In a doubleblind, randomized, placebo-controlled intervention study of 144 women of child-bearing age, 5-MTHF supplementation resulted in a greater accumulation of 5-MTHF in red blood cells than equimolar doses of folic acid. Activated B vitamins provide methyl groups to support healthy methylation, a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, hormone and neurotransmitter production, and energy metabolism. Neuronal Health:
Research suggests that B vitamins help maintain healthy nervous system function. In a randomized controlled study, a combination of methylfolate, methycobalamin and pyridoxal-5phosphate promoted healthy epidermal nerve fiber density and nerve comfort. These vitamins also enhance healthy endothelial function and play a vital role in the metabolism of homocysteine.