Progressive Labs BRM4 250 mg supports by promoting white blood cell production to fend off invaders in the body. Immune support. BRM4 has been shown to support natural killer (NK) cell activity, natural production of cytokynes, (interferon and interleukins), ans supports the activity of lymphocytes. Recommended use: Take 4 capsules before or after a meal, or as directed by a healthcare professional. For best results, the following two-step program is recommended: Step 1: Take 4 capsules 3 times per day for 4 weeks. Step 2: After 4 weeks, reduce dosage to the maintenance level of 4 capsules daily. BRM4 contains Rice Bran Arabinoxylan Compounds (RBAC) that is produced by a patented process using rice bran hemicellulose and shiitake mushroom mycelia. U.S. Patent No. 5560914.