Progressive Labs Fem-Gest offers hormone support for women. Progesterone therapy is used to relieve symptoms of both PMS (when progesterone levels are low and/or estrogen is dominant) and menopause (when both estrogen and progesterone decrease). Recommended use: Gently rub 1/8 to 1/2 tsp. on clean skin, or as directed by a healthcare professional. Apply to belly, thighs, or wrists twice daily. Use 1-2 weeks prior to menstruation each month. Non-menstruating women use any 3 weeks each month. Best results with regular use as directed.