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Gluten Sensitivity Testing Overview
In a person’s quest to be free from chronic disease, many factors will need to be considered including gluten sensitivity. The established medical community has taken a long time to recognize one form of gluten sensitivity, that is celiac disease, as a relatively common problem. They still almost completely ignore all of those who are non-celiac gluten sensitive people.
Blood testing of antibodies related to celiac disease has been around since about 1960 but took another 20 years to be acknowledged at any decent level. The current problem now is that the standard is still only testing for the 33-amino acid chain of one of the proteins (Gliadin MER 33) even though the wheat, rye and barley grains contain hundreds of proteins and many of which can stimulate an antibody response.
Some cling to only tTG and EM antibody testing and then a biopsy if these are positive. Fortunately as of 2011 the decades of research and observation have paid off in the way of relatively simple and definitive tests. I should mention that we still like genetic testing (we use EnteroLab) as well as the blood testing. Genetic tests tells us something about probabilities and the antibody tests tells us what is actually happening.
To help clinicians better diagnose and treat their patients, Cyrex Labs in Phoenix began offering 4 different diagnostic panels related to wheat gluten proteins, other related foods and tests specific for intestinal barrier damage. The different tests are grouped in 4 different Arrays. Array tests 2-4 are blood tests and Array 1 is saliva. The saliva test is cheaper but still misses about 30-50% of gluten sensitivity but still makes sense in some clinical settings. A certain amount of intestinal damage is needed to have a positive blood test. The saliva test can work on infants, for example.
To be tested, we can send you a collection kit. For blood tests you will need to coordinate with a local blood draw center. The saliva test is home administered.
You should know that we don’t mark up lab fees. Also Cyrex Labs has pioneered technology that makes these assays very reasonable in price. You could have had these tests run several years ago but the cost would have been prohibitive for just about everyone.
Cyrex Labs Array 3 tests for autoimmunity and sensitivity in 24 different wheat-related proteins. As of 2011, cost is $325. We recommend this for an initial gluten sensitivity scan. Array 3 along with the previously mentioned genetic test from Enterolab would give excellent, detailed information about wheat gluten sensitivity.
Cyrex Labs Array 4 test for 24 non-wheat foods that can cause autoimmunity and sensitivity as well. This panel was developed to help determine why a person who tests positive with Array 3 and has adopted a gluten-free diet but still is not responding. Cost is $225.
Cyrex Labs Array 2 tests for Intestinal Barrier Damage. Most people with chronic illness will test positive. This is good follow-up tests for your intestinal barrier repair protocols to see how well it is actually working. Cost is $195.
If you are not on a gluten-free diet, you can start with Array 3 to see which wheat related grains are having a negative effect. If you are gluten-free and still not well, you will want to run Array 4 to see what else might be causing problems. This would be a good time to assess your intestinal barrier integrity.
Follow this link for Health Resources:Cyrex Lab Procedures
Blood testing of antibodies related to celiac disease has been around since about 1960 but took another 20 years to be acknowledged at any decent level. The current problem now is that the standard is still only testing for the 33-amino acid chain of one of the proteins (Gliadin MER 33) even though the wheat, rye and barley grains contain hundreds of proteins and many of which can stimulate an antibody response.
Some cling to only tTG and EM antibody testing and then a biopsy if these are positive. Fortunately as of 2011 the decades of research and observation have paid off in the way of relatively simple and definitive tests. I should mention that we still like genetic testing (we use EnteroLab) as well as the blood testing. Genetic tests tells us something about probabilities and the antibody tests tells us what is actually happening.
To help clinicians better diagnose and treat their patients, Cyrex Labs in Phoenix began offering 4 different diagnostic panels related to wheat gluten proteins, other related foods and tests specific for intestinal barrier damage. The different tests are grouped in 4 different Arrays. Array tests 2-4 are blood tests and Array 1 is saliva. The saliva test is cheaper but still misses about 30-50% of gluten sensitivity but still makes sense in some clinical settings. A certain amount of intestinal damage is needed to have a positive blood test. The saliva test can work on infants, for example.
To be tested, we can send you a collection kit. For blood tests you will need to coordinate with a local blood draw center. The saliva test is home administered.
You should know that we don’t mark up lab fees. Also Cyrex Labs has pioneered technology that makes these assays very reasonable in price. You could have had these tests run several years ago but the cost would have been prohibitive for just about everyone.
Cyrex Labs Array 3 tests for autoimmunity and sensitivity in 24 different wheat-related proteins. As of 2011, cost is $325. We recommend this for an initial gluten sensitivity scan. Array 3 along with the previously mentioned genetic test from Enterolab would give excellent, detailed information about wheat gluten sensitivity.
Cyrex Labs Array 4 test for 24 non-wheat foods that can cause autoimmunity and sensitivity as well. This panel was developed to help determine why a person who tests positive with Array 3 and has adopted a gluten-free diet but still is not responding. Cost is $225.
Cyrex Labs Array 2 tests for Intestinal Barrier Damage. Most people with chronic illness will test positive. This is good follow-up tests for your intestinal barrier repair protocols to see how well it is actually working. Cost is $195.
If you are not on a gluten-free diet, you can start with Array 3 to see which wheat related grains are having a negative effect. If you are gluten-free and still not well, you will want to run Array 4 to see what else might be causing problems. This would be a good time to assess your intestinal barrier integrity.
Follow this link for Health Resources:Cyrex Lab Procedures
