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Home . Popular Brands . Douglas Laboratories . Homocystrol + TMG 90c
Homocystrol + TMG 90c

Douglas Laboratories Homocystrol + TMG supports healthy homocysteine metabolism and metabolic processes that require methyl donation. Homocysteinemia, or elevated plasma homocysteine, is a major factor that can influence poor cardiovascular health. High plasma levels of homocysteine appear to have negative effects on the vasculature, impairing the functional abilities of endothelial and smooth muscle cells. Suboptimal intake of several B vitamins, renal failure, environment, diet, stress, and genetic defects in homocysteine metabolism can all contribute to abnormal homocysteine levels. Homocysteine is a sulfur containing amino acid that is created in the body from methionine, an essential amino acid derived solely from dietary intake. Methionine is metabolized into homocysteine via an intermediate, Sadenosylmethionine. Homocysteine can be metabolized to produce cysteine, a nonessential sulfur-containing amino acid, or it can be remethylated to methionine. Whether the body needs cysteine or methionine will dictate which path homocysteine metabolism will take.
Production of cysteine from homocysteine requires two specific enzymes for which vitamin B-6 is an essential coenzyme. Without adequate vitamin B-6, homocysteine cannot be metabolized into cysteine. The body can also metabolize homocysteine by remethylating it to methionine. The primary route by which homocysteine is remethylated to methionine requires folate in the form of methyltetrahydrofolate as a methyl donor and vitamin B-12 (methylcobalamin) as a coenzyme. Methyltetrahydrofolate, or L-methylfolate, is synthesized in the body from dietary folic acid. However, L-methylfolate can be used directly by the body, without the need for folic acid conversion via the enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR). In certain populations, the body’s ability to convert folic acid to 5-MTHF by use of this enzyme may be compromised due to genetic differences.
Recommended Use: Take 3 capsules daily, in divided doses, or as directed by a healthcare professional.

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Homocystrol + TMG 90c
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Homocystrol + TMG 90c

Item #: DLHomocystrolTMG
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Our Price:$32.1032.1
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Douglas Laboratories Homocystrol + TMG supports healthy homocysteine metabolism and metabolic processes that require methyl donation. Homocysteinemia, or elevated plasma homocysteine, is a major factor that can influence poor cardiovascular health. High plasma levels of homocysteine appear to have negative effects on the vasculature, impairing the functional abilities of endothelial and smooth muscle cells. Suboptimal intake of several B vitamins, renal failure, environment, diet, stress, and genetic defects in homocysteine metabolism can all contribute to abnormal homocysteine levels. Homocysteine is a sulfur containing amino acid that is created in the body from methionine, an essential amino acid derived solely from dietary intake. Methionine is metabolized into homocysteine via an intermediate, Sadenosylmethionine. Homocysteine can be metabolized to produce cysteine, a nonessential sulfur-containing amino acid, or it can be remethylated to methionine. Whether the body needs cysteine or methionine will dictate which path homocysteine metabolism will take.
Production of cysteine from homocysteine requires two specific enzymes for which vitamin B-6 is an essential coenzyme. Without adequate vitamin B-6, homocysteine cannot be metabolized into cysteine. The body can also metabolize homocysteine by remethylating it to methionine. The primary route by which homocysteine is remethylated to methionine requires folate in the form of methyltetrahydrofolate as a methyl donor and vitamin B-12 (methylcobalamin) as a coenzyme. Methyltetrahydrofolate, or L-methylfolate, is synthesized in the body from dietary folic acid. However, L-methylfolate can be used directly by the body, without the need for folic acid conversion via the enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR). In certain populations, the body’s ability to convert folic acid to 5-MTHF by use of this enzyme may be compromised due to genetic differences.
Recommended Use: Take 3 capsules daily, in divided doses, or as directed by a healthcare professional.
Douglas Laboratories Homocystrol + TMG Facts:

3 vegetarian capsules contain:

  • Riboflavin (as Riboflavin-5-Phosphate) 50 mg
  • Vitamin B6 (as Pyridoxal-5-Phosphate) 50 mg
  • Folate (as L-methylfolate, Metafolin) 800 mcg
  • Vitamin B12 (methylcobalamin) 1,000 mcg
  • Magnesium (as Magnesium Chelate) 50 mg
  • Trimethylglycine (Betaine) 1,000 mg
  • Choline (as Choline Bitartrate) 150 mg
Other ingredients: Hydroxypropyl methylcellulose (capsule), cellulose, vegetable stearate, and silica.
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